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Sept. 25, 2023

Demystifying COVID-19: Dr. Choctaw’s Deep Dive into mRNA Vaccines and the Future of Nasal Spray Immunizations

Demystifying COVID-19: Dr. Choctaw’s Deep Dive into mRNA Vaccines and the Future of Nasal Spray Immunizations

Get set to revolutionize your understanding of COVID-19 vaccines, as we go under the microscope with Dr. William T. Choctaw, a seasoned surgeon with five decades of experience. Our enlightening tête-à-tête will offer you a deep dive into the innovati...

Get set to revolutionize your understanding of COVID-19 vaccines, as we go under the microscope with Dr. William T. Choctaw, a seasoned surgeon with five decades of experience. Our enlightening tête-à-tête will offer you a deep dive into the innovative world of mRNA vaccines, their mechanism, and its potential to change the face of vaccine pharmacology. Not just that, we'll also unravel the differences between influenza and COVID-19 vaccines, and how our body’s cells memorize and react.

Ever imagined a vaccine without needles? Yes, you heard it right. Together, we will explore the promising future of nasal spray vaccines and their ease of administration, especially beneficial for those needle-wary among us. Plus, we're also decoding the crucial differences between a common cold and flu, and why recognizing these symptoms can make a world of difference. The pivotal role of preventive measures - masking, distancing, and hand washing - is also on our list. So, tune in for this riveting discussion, as we dissect the science behind vaccines, their preventive power, and the groundbreaking advancements in the field of COVID-19 vaccination.

Choctaw Medical Group, Inc.
Healthcare Quality Leadership Education Group

Bernie Brown, ESQ
Author A Prosecutor's Analysis of Personal Supernatural Experiences

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The Host, Dr. William Choctaw; MD, JD, is a healthcare leadership expert, possessing a Medical Doctorate from the Yale University School of Medicine, and a Jurist Doctorate from Western University. Over a span of 50 years practicing medicine, he has served as Chief of Staff, Chief of Surgery, and as a member of the medical executive committee at Citrus Valley Medical Center over a 10 year period. Also, while practicing at Citrus Valley Medical Center, he served as Chief Transformation Officer, (developed a Robust Process Improvement/Lean Six Sigma program). Dr. Choctaw lectures nationally and internationally on medical leadership issues for hospital staffs, executives, and managers. He served as a Physician Surveyor on the Joint Commission. He's the author of 2 books, "Medical Malpractice: A Physician's Guide to the Law" and "Transforming the Patient Experience: A New Paradigm for Hospital and Physician Leadership, published by the Springer Publishing Co. He’s the President of Choctaw Medical Group, Inc., a clinical practice and medical legal consulting firm for medical staff executives, physician leaders, and hospitals.

Transcript
1 00:00:00,821 --> 00:00:03,490 Speaker 1: Coming up on this episode of the HWWP. 2 00:00:04,682 --> 00:00:09,960 Speaker 2: There is no vaccine that can kill the virus directly 3 00:00:09,960 --> 00:00:13,871 , and what I mean by that is that's not how vaccines operate. 4 00:00:13,871 --> 00:00:16,527 They don't go in and kill the virus or kill the bacteria or 5 00:00:16,568 --> 00:00:16,910 whatever. 6 00:00:17,201 --> 00:00:20,196 Speaker 1: This podcast episode is sponsored by Choctaw Medical 7 00:00:20,216 --> 00:00:23,737 Group Incorporated. Also sponsored by Bernie Brown 8 00:00:23,859 --> 00:00:27,553 Esquire, author of a Prosecutor's Analysis of 9 00:00:27,655 --> 00:00:30,628 Personal Supernatural Experiences. A collection of 10 00:00:30,708 --> 00:00:34,969 fascinating stories awaiting your verdict Fact, fiction, 11 00:00:35,491 --> 00:00:39,456 fabrication or fantasy, available in paperback and 12 00:00:39,476 --> 00:00:46,764 digital formats. Go to THWWPcom to get your copy. Welcome to the 13 00:00:46,764 --> 00:00:49,390 Healthy, wealthy and Wise podcast with Dr William T 14 00:00:49,450 --> 00:00:53,496 Choctaw, mdjd, where the doctor helps you unlock your full 15 00:00:53,536 --> 00:00:57,594 potential by equipping you with tools and knowledge in the areas 16 00:00:57,594 --> 00:01:01,435 of health, wealth and wisdom, anchored in his experience as a 17 00:01:01,536 --> 00:01:04,718 business executive, a physician surveyor for the Joint 18 00:01:04,737 --> 00:01:09,457 Commission, a former mayor and over 50 years of experience as a 19 00:01:09,457 --> 00:01:13,581 general surgeon. You've got questions, he's got answers, so 20 00:01:13,621 --> 00:01:17,980 let's get started. Here's Dr William T Choctaw, mdjd. 21 00:01:19,103 --> 00:01:22,626 Speaker 2: Good morning. I'm Dr William T Choctaw and I will be 22 00:01:22,668 --> 00:01:25,986 your host today. Welcome to the Healthy, wealthy and Wise 23 00:01:26,106 --> 00:01:29,989 podcast. Each month, we strive to provide you, our listeners, 24 00:01:30,120 --> 00:01:33,320 with mental, physical and spiritual strength by giving 25 00:01:33,501 --> 00:01:38,480 actionable advice and tips, guidance and information to help 26 00:01:38,480 --> 00:01:42,430 you achieve your own personal, professional and spiritual goals 27 00:01:42,430 --> 00:01:47,510 . We consider the health of the mind, body and spirit paramount, 28 00:01:47,510 --> 00:01:52,271 as a single unit that can provide a cumulative strength 29 00:01:53,000 --> 00:01:56,890 greater than the individual parts to strengthen the whole 30 00:01:56,950 --> 00:02:02,408 person. So today, sit back and enjoy and come along on a very 31 00:02:02,468 --> 00:02:07,442 exciting journey with us. Today, we're going to be talking about 32 00:02:07,442 --> 00:02:14,205 our COVID-19 spray vaccines coming soon. Our COVID-19 spray 33 00:02:14,265 --> 00:02:19,818 vaccines coming soon. As always, we like to start off with my 34 00:02:19,838 --> 00:02:25,231 beliefs. I believe life is about being of service to others. I 35 00:02:25,272 --> 00:02:28,859 believe knowledge is power. I believe leaders can change the 36 00:02:28,878 --> 00:02:32,792 world. We like to give you an outline. This basically tells 37 00:02:32,812 --> 00:02:35,771 you what we're going to talk about and, as importantly, it'll 38 00:02:35,771 --> 00:02:38,769 let you know when we're just about done. You know you're very 39 00:02:38,769 --> 00:02:43,145 , very busy people with a lot on your plate, and so we are very 40 00:02:43,205 --> 00:02:48,122 grateful and are pleased and humbled that you've chosen to 41 00:02:48,163 --> 00:02:51,602 spend a few minutes of your valuable time with us. We're 42 00:02:51,622 --> 00:02:54,830 going to talk about the new COVID vaccine that's coming soon 43 00:02:54,830 --> 00:02:58,905 and that may already be available. We're going to talk 44 00:02:58,944 --> 00:03:03,524 about the influenza versus COVID vaccines and how they differ 45 00:03:03,944 --> 00:03:08,044 both in terms of type, quality and methodology. We'll talk 46 00:03:08,085 --> 00:03:13,104 about messenger RNA and how this novel approach to the COVID 47 00:03:13,145 --> 00:03:20,409 vaccine has changed forever vaccine pharmacology going 48 00:03:20,469 --> 00:03:24,735 forward. And we'll talk some about prevention in terms of 49 00:03:24,794 --> 00:03:30,942 helping you to stay safe. Well, we know that every year now we 50 00:03:31,042 --> 00:03:37,530 have what we call a tri-endemic influenza, and what that means 51 00:03:37,631 --> 00:03:41,187 is we have a tri-endemic. We have three different types of 52 00:03:41,227 --> 00:03:46,030 viruses that may very well cause infection in any one of us in 53 00:03:46,169 --> 00:03:50,689 any given year. One is the respiratory sensitional virus, 54 00:03:51,420 --> 00:03:54,389 which does not affect a lot of people most of the young but 55 00:03:54,430 --> 00:03:59,341 does occur. The influenza virus, which is the most common, and 56 00:03:59,381 --> 00:04:04,605 then, of course, the coronavirus , the COVID-19 virus, and so 57 00:04:04,626 --> 00:04:08,086 we're going to look at how individuals can protect 58 00:04:08,127 --> 00:04:12,663 themselves, and we're going to primarily focus on the flu 59 00:04:13,145 --> 00:04:17,942 influenza virus and the COVID-19 influenza virus. Just remember 60 00:04:18,425 --> 00:04:22,266 the basics of what works for all of those is masking, wearing 61 00:04:22,305 --> 00:04:26,809 mask distance at least six feet apart if possible, and hand 62 00:04:26,829 --> 00:04:31,324 washing. Those basics have not changed and please keep that in 63 00:04:31,365 --> 00:04:35,862 mind. Survival from any type of viral infection, certainly in a 64 00:04:35,922 --> 00:04:40,661 pandemic, depends on prevention and treatment. Prevention is 65 00:04:40,742 --> 00:04:44,362 important to hopefully prevent others from getting it or 66 00:04:44,403 --> 00:04:49,324 preventing the individual from getting it again. Treatment is 67 00:04:49,504 --> 00:04:53,041 for you to get over the illness that you have. But it's 68 00:04:53,081 --> 00:04:58,247 important to keep in mind that vaccines primarily deal with 69 00:04:58,327 --> 00:05:06,387 prevention. The way I like to think about it is that it's a 70 00:05:06,447 --> 00:05:13,189 preventive prevention. There is no vaccine that can kill the 71 00:05:13,250 --> 00:05:17,968 virus directly. What I mean by that is that's not how vaccines 72 00:05:18,089 --> 00:05:20,406 operate. They don't go in and kill the virus or kill the 73 00:05:20,425 --> 00:05:25,300 bacteria or whatever. Basically, what they do, which is 74 00:05:25,360 --> 00:05:30,487 ingenious, is that they go in, the vaccines stimulate the body 75 00:05:31,067 --> 00:05:37,346 to produce antibodies or its own mechanism and the cells in the 76 00:05:37,386 --> 00:05:41,605 body basically kill the vaccine. Again, vaccines deal primarily 77 00:05:41,646 --> 00:05:44,483 with prevention and not treatment. We'll talk about 78 00:05:44,502 --> 00:05:47,985 treatment a bit later on in this discussion, but as we talk 79 00:05:48,024 --> 00:05:51,983 about vaccines, we're talking about prevention. Administration 80 00:05:51,983 --> 00:05:55,142 of the vaccines basically are two ways. We're talking about 81 00:05:55,202 --> 00:06:00,288 flu and COVID vaccines. Those two ways are needle with an 82 00:06:00,329 --> 00:06:05,149 injection in the arm, intramuscularly, and nasal spray 83 00:06:05,149 --> 00:06:08,240 . We're going to look at for this presentation. We're going 84 00:06:08,261 --> 00:06:12,901 to look at the delivery mechanism for vaccines Needle, 85 00:06:12,922 --> 00:06:17,423 the more traditional approach, or nasal spray we're primarily 86 00:06:17,463 --> 00:06:21,543 going to look at the regular flu that occurs every year in 87 00:06:21,682 --> 00:06:25,762 influenza and COVID-19, which has been with us for 88 00:06:25,783 --> 00:06:29,685 approximately the last four years. Let's start with the flu 89 00:06:29,939 --> 00:06:33,204 Now. We're all familiar with the flu. We've all had it over the 90 00:06:33,245 --> 00:06:38,302 last many, many years. But let's start even more basic. Before 91 00:06:38,362 --> 00:06:42,648 you get the flu, many of us get what we call COLS, c-o-l-d. 92 00:06:45,365 --> 00:06:48,983 What's the difference between a cold and the flu? Well, with the 93 00:06:48,983 --> 00:06:52,944 cold, you have mild respiratory symptoms. You may have mild 94 00:06:53,004 --> 00:06:59,846 fatigue. Onset tends to be gradual. You may have some 95 00:06:59,947 --> 00:07:04,064 headache or some nasal discomfort. With the flu, on the 96 00:07:04,064 --> 00:07:07,906 other hand, you take all those things and you've doubled them 97 00:07:07,966 --> 00:07:11,927 by five to 10 times. In essence, the way I like to think about 98 00:07:11,968 --> 00:07:18,966 it, a fluenza is a very, very, very serious cold. A fluenza is 99 00:07:19,007 --> 00:07:23,607 a very, very serious cold. Influencers are associated with 100 00:07:23,927 --> 00:07:29,209 severe symptoms, oftentimes muscle body aches throughout the 101 00:07:29,209 --> 00:07:35,004 body, usually with a sudden onset, and can involve a fever, 102 00:07:35,144 --> 00:07:40,869 exhaustion or loss of appetite. So, cold symptoms, flu symptoms 103 00:07:41,759 --> 00:07:46,127 let's go a little deeper Flu symptoms and let's compare them 104 00:07:47,560 --> 00:07:53,466 to what we're talking about with COVID-19, which clearly can get 105 00:07:53,466 --> 00:07:58,548 into respiratory difficulties, shortness of breath, inability 106 00:07:58,588 --> 00:08:02,528 to breathe and all the other problems that can be associated 107 00:08:02,588 --> 00:08:06,629 with that. So when we look at, okay, how do we prevent this 108 00:08:06,689 --> 00:08:11,942 from happening? So what is our basic prevention mechanism? Well 109 00:08:11,942 --> 00:08:17,992 , those mechanisms tend to be vaccinations and with the 110 00:08:18,031 --> 00:08:21,353 traditional injection, needle injection, we have to go to a 111 00:08:21,392 --> 00:08:26,834 facility, a medical type facility, either inpatient or 112 00:08:26,894 --> 00:08:32,192 outpatient, and they inject us with the medication With the 113 00:08:32,292 --> 00:08:38,894 nasal spray. You can do it at home. So this would be a huge 114 00:08:39,616 --> 00:08:46,133 lift for individuals who have to get vaccinations for COVID. So 115 00:08:46,173 --> 00:08:49,214 with the nasal spray, basically we're talking about no needles, 116 00:08:49,534 --> 00:08:55,179 basically no pain. That's really another step forward in this 117 00:08:55,259 --> 00:09:00,052 whole march toward providing better care for all of us. So 118 00:09:00,131 --> 00:09:06,751 far in this country there's only one nasal spray vaccine that's 119 00:09:06,792 --> 00:09:11,091 been approved by the FDA, the Federal Drug Administration, and 120 00:09:11,091 --> 00:09:14,854 that's for the influenza, that's for the flu. Presently, 121 00:09:15,034 --> 00:09:18,993 as of today and we're in September right now there is no 122 00:09:19,092 --> 00:09:25,333 known FDA-approved nasal spray vaccine for COVID. But those are 123 00:09:25,333 --> 00:09:28,413 coming and we'll talk about that a bit later. But let's look 124 00:09:28,413 --> 00:09:31,452 at the flu miss and what have we learned? Well, flu miss 125 00:09:31,472 --> 00:09:36,076 contains a weak and strain of the virus, of the flu virus, 126 00:09:37,511 --> 00:09:41,611 that's made into a spray that's injected into the nose, sprayed 127 00:09:41,652 --> 00:09:44,937 into the nose. That then triggers the nose and the body's 128 00:09:44,937 --> 00:09:49,995 response to improve its immune system and build antibodies to 129 00:09:50,054 --> 00:09:53,532 stop us from getting the flu. Let me say that again Flu miss 130 00:09:54,173 --> 00:09:59,335 is a nasal spray vaccine for the flu, only influenza that is 131 00:09:59,414 --> 00:10:03,596 injected into the nose, that triggers an immune response in 132 00:10:03,615 --> 00:10:08,931 the nose and the body to build antibodies that prevents us from 133 00:10:08,931 --> 00:10:13,255 getting the flu again or that particular strain of the flu. 134 00:10:14,671 --> 00:10:17,974 Contraindications to the flu miss, this nasal spray vaccine 135 00:10:18,014 --> 00:10:22,057 for the flu only one contraindication is pregnant 136 00:10:22,076 --> 00:10:26,333 women, and part of that reason obviously may be that the fact 137 00:10:26,374 --> 00:10:30,815 that you are injecting an old virus, a dead virus or something 138 00:10:30,815 --> 00:10:35,052 that may create problems for pregnant women. And the second 139 00:10:35,734 --> 00:10:40,254 is in patients who have an immune system, an immune 140 00:10:40,355 --> 00:10:44,331 protection system, that there's always a risk, obviously, if 141 00:10:44,351 --> 00:10:46,692 you're going to inject something in them, even though it may be 142 00:10:46,753 --> 00:10:51,791 weakened, but if they have a weakened system themselves, that 143 00:10:51,791 --> 00:10:56,035 may significantly increase their risk. So we've talked 144 00:10:56,076 --> 00:11:01,712 about the mechanism, the vehicle for vaccination. First with the 145 00:11:01,712 --> 00:11:08,130 flu, only one that has a spray. Now let's go to COVID. One of 146 00:11:08,150 --> 00:11:11,653 the things that you may not have recognized a few years ago a 147 00:11:11,673 --> 00:11:15,154 couple of years ago, basically, when the vaccines first came out 148 00:11:15,154 --> 00:11:20,518 with COVID is that they came about with the use of a novel 149 00:11:20,599 --> 00:11:25,619 new approach, and this was what's called the messenger RNA 150 00:11:25,679 --> 00:11:30,113 approach, and so let's take a closer look at that. Why is that 151 00:11:30,113 --> 00:11:34,591 such a big deal? One of the reasons it's a big deal is that 152 00:11:34,611 --> 00:11:38,931 vaccines used to take years to actually come online. It took 153 00:11:39,032 --> 00:11:42,331 years and, needless to say, we were all in a crisis talking 154 00:11:42,350 --> 00:11:45,995 about the world now, the world pandemic and so it was important 155 00:11:45,995 --> 00:11:49,909 to get those vaccines and get vaccines as fast as possible. So 156 00:11:49,909 --> 00:11:53,750 you had pharmaceutical and medical facilities working 157 00:11:53,791 --> 00:11:57,693 around the country, around the world, to come up with a safe 158 00:11:57,995 --> 00:12:03,452 and effective vaccine to save people's lives, and this was 159 00:12:03,533 --> 00:12:08,269 done. This was done and it was done because it was decided to 160 00:12:08,451 --> 00:12:11,900 use this new approach that, instead of the traditional way 161 00:12:12,190 --> 00:12:18,991 of using old virus or dead virus in small amounts to stimulate 162 00:12:20,375 --> 00:12:24,534 new antibiotic production, it was decided to use just a 163 00:12:24,615 --> 00:12:30,034 molecule of messenger RNA, which had nothing to do with the 164 00:12:30,054 --> 00:12:36,610 virus, just a molecule messenger RNA. Put that into a cell and 165 00:12:36,649 --> 00:12:42,370 then take that information that has been made in the cell and 166 00:12:42,530 --> 00:12:46,812 use that to stimulate the immune system. One of the things that 167 00:12:46,852 --> 00:12:53,580 this did, or confirm, is that our cells have memory. Think 168 00:12:53,639 --> 00:12:58,331 about that Our cells, cells in our body have memory. Now, we're 169 00:12:58,331 --> 00:13:01,995 made up of billions of cells, billions and billions of cells, 170 00:13:02,970 --> 00:13:07,895 but each one of them has memory that if you inject something 171 00:13:08,037 --> 00:13:15,090 into them directly or indirectly , as in the case with mRNA, that 172 00:13:15,090 --> 00:13:19,850 the cell can remember what message you left for them and 173 00:13:19,889 --> 00:13:23,474 can then actually act accordingly if they're invaded a 174 00:13:23,474 --> 00:13:24,216 second time. 175 00:13:25,573 --> 00:13:28,533 Speaker 1: This podcast episode is sponsored by Choctaw Medical 176 00:13:28,572 --> 00:13:32,096 Group Incorporated. Also sponsored by Bernie Brown 177 00:13:32,236 --> 00:13:35,909 Esquire, author of a Prosecutor's Analysis of 178 00:13:36,010 --> 00:13:38,971 Personal Supernatural Experiences. A collection of 179 00:13:39,052 --> 00:13:43,333 fascinating stories awaiting your verdict Fact, fiction, 180 00:13:43,835 --> 00:13:48,076 fabrication or fantasy, available in paperback and 181 00:13:48,115 --> 00:13:54,932 digital formats. Go to THWWPcom to get your copy, absolutely 182 00:13:54,972 --> 00:13:55,534 extraordinary. 183 00:13:56,230 --> 00:13:58,750 Speaker 2: So how does this mRNA stuff really work? What the 184 00:13:58,770 --> 00:14:02,573 coronavirus is like is one of those calls one of the causes of 185 00:14:02,573 --> 00:14:07,472 COVID-19 and was named for this crown-like spike on the surface 186 00:14:07,472 --> 00:14:10,895 called spike proteins. These are spikes that are on the virus 187 00:14:10,895 --> 00:14:13,870 itself and if you've ever seen pictures of the virus, it's like 188 00:14:13,870 --> 00:14:17,051 a ball with a lot of little spiky things on it. Well, that's 189 00:14:17,051 --> 00:14:21,456 important because there's those little spiky things that the 190 00:14:22,178 --> 00:14:28,947 vaccine can attack and does attack and ends up taking part 191 00:14:28,988 --> 00:14:35,154 of that material with mRNA. Put it into a normal cell and have 192 00:14:35,216 --> 00:14:41,323 that cell replicate that spiky protein type of substance and 193 00:14:41,403 --> 00:14:44,735 put it into the cell's memory so that the cell can then protect 194 00:14:44,796 --> 00:14:50,326 itself in future attacks. What's different about, again, this 195 00:14:50,447 --> 00:14:54,289 mRNA approach as compared to the traditional approach, is that 196 00:14:55,091 --> 00:14:59,423 this new approach does not contain any virus, small or 197 00:14:59,482 --> 00:15:06,312 large. This is completely novel or different from any virus. And 198 00:15:06,312 --> 00:15:10,346 the second thing is when the body responds. It can. Sometimes 199 00:15:10,346 --> 00:15:14,775 you may have like a mild reaction to the vaccine, just 200 00:15:14,816 --> 00:15:18,942 like you normally do with flu vaccine, but usually it's very 201 00:15:18,981 --> 00:15:22,519 mild a little fever, maybe a little headache, a few tears, 202 00:15:23,413 --> 00:15:27,557 but usually that goes away. But what I want you to remember is 203 00:15:27,830 --> 00:15:31,293 number one. Yourselves have memory. Number two I believe 204 00:15:31,654 --> 00:15:35,857 that the work of the scientists and doctors and epidemiologists 205 00:15:35,918 --> 00:15:40,769 and others that come up with this new mRNA process for 206 00:15:40,809 --> 00:15:44,836 vaccination for the coronavirus is just absolutely extraordinary 207 00:15:44,836 --> 00:15:48,852 . And so if we drill down a little more about this mRNA 208 00:15:48,893 --> 00:15:53,657 process, we notice that again, when the mRNA, messenger RNA 209 00:15:53,850 --> 00:15:58,274 that's what mRNA stands for goes into the cell, it does not go 210 00:15:58,354 --> 00:16:03,115 into nucleus. Now let's back up. Let's imagine that a cell is 211 00:16:03,154 --> 00:16:06,850 like an egg. The center part of the egg is the yolk, that's the 212 00:16:06,910 --> 00:16:09,956 yellow part. What's around the egg? Let's see if you fry it. 213 00:16:10,889 --> 00:16:13,392 What's around the egg is white material. We'll call that 214 00:16:13,452 --> 00:16:17,217 cytoplasm. And then, of course, the egg is normally in a shell 215 00:16:18,230 --> 00:16:24,798 before you crack it and put it in a pan. The messenger RNA does 216 00:16:24,798 --> 00:16:30,753 not go into the yolk part of the egg. It stays in the white 217 00:16:30,812 --> 00:16:34,149 part around the center of the egg. Why is that important? The 218 00:16:34,210 --> 00:16:38,979 center of the egg, the yolk, the nucleus is where the DNA is. 219 00:16:39,630 --> 00:16:42,452 That's where the message for life, that's where the 220 00:16:42,493 --> 00:16:48,321 distinction between each of us is developed and recorded. 221 00:16:48,629 --> 00:16:52,798 That's in the nucleus. This messenger RNA does this work in 222 00:16:52,817 --> 00:16:56,097 the periphery, in the white part surrounding the yellow yolk, 223 00:16:57,030 --> 00:17:00,153 and that's where it does its work. That's where it replicates 224 00:17:00,153 --> 00:17:06,230 and transcribes this foreign protein called coronavirus and 225 00:17:06,592 --> 00:17:10,615 strengthens the cell for future battle. At Yale University, at 226 00:17:10,654 --> 00:17:14,876 the School of Engineering and Applied Science, professor Mark 227 00:17:15,057 --> 00:17:21,000 Saltzman and others have been working on an mRNA, but as a 228 00:17:21,663 --> 00:17:25,479 nasal spray, instead of getting the injections for your vaccine 229 00:17:27,089 --> 00:17:31,332 based on mRNA. They, along with many others, I might add, there 230 00:17:31,352 --> 00:17:35,213 are other labs around the country, around the world, that 231 00:17:35,233 --> 00:17:39,291 are working on this and are working on a spray that allows 232 00:17:39,332 --> 00:17:41,830 you the same degree of protection using the same 233 00:17:41,891 --> 00:17:49,219 process, the mRNA process and basically the mRNA is able to 234 00:17:51,844 --> 00:17:57,442 attack this spiked part of the virus replicated within the cell 235 00:17:57,442 --> 00:18:02,760 in the cytoplasm, not in the nucleus and then allow that cell 236 00:18:02,760 --> 00:18:05,863 to then to be able to create its own antibodies, which are 237 00:18:05,883 --> 00:18:11,239 like foot soldiers that fight infection of any type. The idea 238 00:18:11,278 --> 00:18:16,020 of a nasal spray is very good and is attractive because it is 239 00:18:16,261 --> 00:18:19,780 injected directly into the nose, which is where the virus begins 240 00:18:19,780 --> 00:18:23,878 . We're certainly where it does most of its damage. It just 241 00:18:23,939 --> 00:18:27,102 makes sense that if you can take something and you put it where 242 00:18:27,342 --> 00:18:31,178 most of the virus lives or is going to be, that allows it to 243 00:18:31,218 --> 00:18:37,483 be even more effective. Keep in mind it's through the nose and 244 00:18:37,503 --> 00:18:45,383 the mouth, when we cough, sneeze , breathe, yell, sing, etc. Is 245 00:18:45,403 --> 00:18:49,461 how we spread the virus. There are many labs around the world 246 00:18:49,923 --> 00:18:53,162 that are working on nasal sprays as a vaccine for the 247 00:18:53,201 --> 00:18:59,260 Coronavirus of COVID-19. The lab in India, the codeogenics lab 248 00:18:59,300 --> 00:19:03,557 in the US University of Hong Kong lab in China and our own 249 00:19:03,616 --> 00:19:07,896 National Institute of Health here in the United States. One 250 00:19:07,936 --> 00:19:11,298 of the things that's very unique about this mRNA approach is 251 00:19:11,338 --> 00:19:19,227 that the package or the delivery system of this particular virus 252 00:19:19,227 --> 00:19:24,934 , this particular spray, and the information in this spray, the 253 00:19:25,035 --> 00:19:31,395 mRNA, is encased in a nano-particle delivery system. I 254 00:19:31,395 --> 00:19:34,981 know that's quite a bit, but nano means something that's real 255 00:19:34,981 --> 00:19:38,903 , real small. It's a special delivery system that prevents 256 00:19:39,536 --> 00:19:43,654 the particle from being injured or destroyed by the body Because 257 00:19:43,654 --> 00:19:46,183 , remember, the body does not like any foreign invasion. 258 00:19:47,297 --> 00:19:50,220 Anything comes into the body, the antibodies are going to be 259 00:19:50,319 --> 00:19:53,417 on alert and they're going to go after it. You have to couch it 260 00:19:53,519 --> 00:19:58,137 in a way that it can escape and slip through those normal 261 00:19:58,178 --> 00:20:02,557 defenses of the body so that it can be delivered into the areas 262 00:20:02,616 --> 00:20:05,704 of the lung and parts of the respiratory system that would 263 00:20:05,744 --> 00:20:10,663 then allow it to be in place to stimulate those same antibodies 264 00:20:11,163 --> 00:20:14,960 to fight future invaders, particularly coronavirus 265 00:20:15,020 --> 00:20:18,582 invaders. Transcription is an important part of what the 266 00:20:18,622 --> 00:20:22,577 messenger RNA does, just very, very quickly. Transcription just 267 00:20:22,577 --> 00:20:27,583 means it copies. It's able to copy information from this 268 00:20:28,684 --> 00:20:33,565 coronavirus, give it to the cell outside of the nucleus of the 269 00:20:33,625 --> 00:20:38,442 cell and allow the body to produce the same information and 270 00:20:38,442 --> 00:20:42,298 create antibodies to that information. A quick word about 271 00:20:42,338 --> 00:20:45,279 the most recent variant, the most recent variants name is 272 00:20:45,460 --> 00:20:52,278 ERIS. It is different from other coronavirus strains in that it 273 00:20:52,378 --> 00:20:56,057 is causing most of the new strains of coronavirus that 274 00:20:56,117 --> 00:20:59,938 we're now seeing, certainly in this country, since August. 275 00:21:00,038 --> 00:21:05,358 We're now in the month of September, but the good news 276 00:21:05,419 --> 00:21:07,924 about it, though, is that it does not appear to be that 277 00:21:08,025 --> 00:21:11,615 different from previous strains. Why is that important? That's 278 00:21:11,675 --> 00:21:15,944 good news, because it means that the vaccines that are based on 279 00:21:16,005 --> 00:21:21,218 last year's virus should be as effective, if not more effective 280 00:21:21,218 --> 00:21:26,147 , against the upcoming virus that we'll see, mostly in 2024. 281 00:21:27,699 --> 00:21:30,665 Remember, when you take the vaccine in October or so 282 00:21:30,954 --> 00:21:36,643 September, october, November the vaccine is effective and it 283 00:21:36,742 --> 00:21:40,861 peaks three months later. You're taking the vaccine during the 284 00:21:40,921 --> 00:21:45,980 fall to protect you for the virus that we expect to arrive 285 00:21:46,340 --> 00:21:52,799 January, february and March. The other thing about ERIS, the new 286 00:21:52,799 --> 00:21:57,013 variant, and this variant is a sub-variant of the Omicron 287 00:21:57,034 --> 00:21:59,501 variant. I'm sure some of you remember the Omicron variant a 288 00:21:59,541 --> 00:22:02,836 couple of years ago. It was the big, big change. This is a 289 00:22:02,897 --> 00:22:05,880 sub-variant of that, but again it does not appear to be too 290 00:22:05,980 --> 00:22:10,679 different from the Omicron. Consequently, we should be in 291 00:22:10,739 --> 00:22:15,968 good shape, hopefully with the vaccines that we come up with 292 00:22:16,669 --> 00:22:19,656 this year. The latter part of this year, I'm sure you remember 293 00:22:19,656 --> 00:22:24,476 the basic symptoms of COVID-19, fever, fatigue and cough. It 294 00:22:24,516 --> 00:22:27,396 starts off with the respiratory type symptoms, but it is clearly 295 00:22:27,396 --> 00:22:33,300 not limited to the respiratory area. It can cause diarrhea, 296 00:22:33,580 --> 00:22:39,117 gastrointestinal problems, abdominal pain, etc. Depending 297 00:22:39,198 --> 00:22:42,659 on the stage of the disease. Obviously, one of the reasons 298 00:22:42,759 --> 00:22:46,577 why it is so devastating is that it depends on what your 299 00:22:46,637 --> 00:22:51,403 preexisting medical condition is . If you have ongoing medical 300 00:22:51,442 --> 00:22:54,142 problems, and this usually will occur in those of us who are 301 00:22:54,182 --> 00:22:57,823 getting older, then that makes obviously the virus even more 302 00:22:57,883 --> 00:23:02,556 dangerous and makes treatment even more important. Speaking of 303 00:23:02,556 --> 00:23:06,605 treatment, again, leaving aside the prevention treatment, 304 00:23:06,644 --> 00:23:11,222 specifically treatment like Paxovid, which is a medication 305 00:23:11,262 --> 00:23:15,821 you can take as an outpatient, or Redemzavir, which is an IV 306 00:23:15,902 --> 00:23:18,836 medication that you can take also as an outpatient, have been 307 00:23:18,836 --> 00:23:22,884 quite effective in treating the symptoms of COVID if given 308 00:23:23,104 --> 00:23:27,480 early and inappropriately. We're in pretty good shape, but we 309 00:23:27,519 --> 00:23:33,602 want to stay ahead of the curve and kill or destroy this scourge 310 00:23:33,602 --> 00:23:38,457 before it takes more beautiful lives away from us. One of the 311 00:23:38,497 --> 00:23:42,391 things to keep in mind is that COVID does more than just affect 312 00:23:42,391 --> 00:23:46,561 the physical. There's been a huge emotional toll, both on 313 00:23:46,602 --> 00:23:49,788 patients and on caregivers, and on family members and friends. 314 00:23:51,237 --> 00:23:55,164 And remember, as I like to say, the mind, the body and the 315 00:23:55,244 --> 00:23:59,160 spirit are all connected and you cannot affect one part of that 316 00:23:59,220 --> 00:24:03,056 triangle without affecting all parts of that triangle. And so 317 00:24:03,115 --> 00:24:07,063 keep that in mind and be supportive and thoughtful of 318 00:24:07,143 --> 00:24:09,866 individuals who are going through stuff, particularly 319 00:24:09,926 --> 00:24:12,576 health care related stuff, and, even if you don't know the 320 00:24:12,616 --> 00:24:16,865 details, but just give a kind word, handshake, hug, smile, 321 00:24:17,666 --> 00:24:22,282 whatever Because sometimes that itself can be therapeutic and 322 00:24:22,323 --> 00:24:26,278 can be very helpful. In conclusion, flu mist right now 323 00:24:26,439 --> 00:24:30,227 is the only nasal spray vaccine that's been approved by the FDA 324 00:24:30,815 --> 00:24:37,307 and it's only available for the regular flu. All vaccines for 325 00:24:37,367 --> 00:24:40,903 COVID presently are given with an intramuscular injection. 326 00:24:41,414 --> 00:24:45,663 However, many, many labs around the world are working feverishly 327 00:24:45,663 --> 00:24:48,228 and most of them are in the second and third phases of 328 00:24:48,627 --> 00:24:52,321 development, so they should be getting close and not here to 329 00:24:52,342 --> 00:24:57,019 develop the nasal spray variety, which has many advantages that 330 00:24:57,039 --> 00:25:04,487 we've talked about earlier, and it is something that I expect to 331 00:25:04,487 --> 00:25:10,523 be available either the latter part of 2023, or in early 2024. 332 00:25:12,538 --> 00:25:15,526 Speaker 1: This podcast episode is sponsored by Choctaw Medical 333 00:25:15,546 --> 00:25:19,078 Group Incorporated. Also sponsored by Bernie Brown 334 00:25:19,199 --> 00:25:22,885 Esquire, author of a Prosecutor's Analysis of 335 00:25:22,986 --> 00:25:25,938 Personal Supernatural Experiences. A collection of 336 00:25:26,038 --> 00:25:30,298 fascinating stories awaiting your verdict Fact, fiction, 337 00:25:30,798 --> 00:25:35,047 fabrication or fantasy, available in paperback and 338 00:25:35,086 --> 00:25:40,926 digital formats. Go to THWPcom to get your copy. 339 00:25:41,556 --> 00:25:43,701 Speaker 2: And finally, I always like to end on my basic 340 00:25:43,740 --> 00:25:47,759 principles. I like to share this with you. I am a physician of 341 00:25:47,818 --> 00:25:52,458 faith. My first principle is God is in charge, and it's because 342 00:25:52,518 --> 00:25:56,365 of my faith and belief in God in my life that I have been able 343 00:25:56,404 --> 00:25:59,838 to do those things that I've been able to do, and have been 344 00:25:59,939 --> 00:26:05,778 able to receive help and support from others also. Secondly, I 345 00:26:05,818 --> 00:26:08,904 don't have any bad days. Principle number two I learned 346 00:26:08,924 --> 00:26:12,780 about 20 years, 30 years ago, that the days were good and bad, 347 00:26:12,780 --> 00:26:16,018 or bad whenever I said they were, and so I decided that I 348 00:26:16,057 --> 00:26:18,904 didn't need any more bad days. So my days are the good days are 349 00:26:18,904 --> 00:26:22,041 great days. Principle number three don't sweat the small 350 00:26:22,082 --> 00:26:25,818 stuff, and most stuff is small. I have learned that whenever 351 00:26:25,898 --> 00:26:30,146 things happen that most of times it's usually not nearly as bad 352 00:26:30,186 --> 00:26:34,240 as I think it is. So I'm working on putting things more in 353 00:26:34,299 --> 00:26:38,047 perspective and letting that dictate what my thoughts and 354 00:26:38,067 --> 00:26:41,939 what my actions are. Number four forgiveness is therapy, that 355 00:26:41,979 --> 00:26:47,107 whenever someone does or says something to me that I perceive 356 00:26:47,587 --> 00:26:52,963 as negative, I have learned to forgive instantly. It doesn't 357 00:26:53,003 --> 00:26:56,958 matter what the facts are, just forgive them. And finally, 358 00:26:57,519 --> 00:27:02,548 number four everything is a relationship. Relationships are 359 00:27:02,567 --> 00:27:05,719 based on three things Mutual respect, mutual trust, good 360 00:27:05,759 --> 00:27:09,026 communication. If you have those three things, you have a good 361 00:27:09,066 --> 00:27:14,904 relationship. If you do not, you have work to do. If you like to 362 00:27:14,904 --> 00:27:18,896 subscribe to these podcasts, I would encourage you to go to 363 00:27:19,198 --> 00:27:27,188 wwwbusfraudcom, to 1-0-1-0-0-3. And we would appreciate you 364 00:27:27,228 --> 00:27:34,321 becoming one of our subscribers. Finally, be the change you want 365 00:27:34,321 --> 00:27:39,529 to see in the world. Thank you and have a wonderful day. 366 00:27:40,115 --> 00:27:42,038 Speaker 1: Thank you for listening to this episode of the 367 00:27:42,038 --> 00:27:47,537 Healthy, wet and Wise podcast with Dr William T Chokhtok, mdjd 368 00:27:47,537 --> 00:27:51,142 . Be sure to check out other great episodes covering areas of 369 00:27:51,142 --> 00:27:57,576 health, wealth and wisdom at THWPcom and, while you're there, 370 00:27:57,576 --> 00:28:01,464 be sure to check out the books, blogs and other literature in 371 00:28:01,484 --> 00:28:04,597 your preferred format, and don't forget to leave a review, 372 00:28:04,917 --> 00:28:11,228 subscribe, share and support the podcast that's at THWPcom. 373 00:28:12,295 --> 00:28:15,421 You've been listening to the Healthy, wet and Wise podcast 374 00:28:15,721 --> 00:28:18,847 with Dr William T Chokhtok, mdjd .
Bernie Brown Profile Photo

Bernie Brown

Retired Assistant Los Angeles City Attorney and book author A Prosecutor's Analysis of Personal Supernatural Experiences

Biography of Bernie Brown

Bernie E. Brown was born in the southern town of Guthrie, Oklahoma. His family moved to Los Angeles, where Bernie grew up as a child. While attending junior high school, Bernie was recognized for his academic achievements and was placed in the College Capable Program. At a young age, Bernie became an entrepreneur, starting a car wash business at the local gas station and running an after school janitorial business while in high school.

Bernie began his college education at Los Angeles City College, where he acquired an Associate of Arts Degree in Speech. In 1972, at the Statewide Intercollegiate Speech Competition, Bernie finished in the top three speakers in the California State Persuasive Speaking Competition after delivering a stunning speech on nuclear disarmament, and he qualified for the National Intercollegiate Competition. Unfortunately, Bernie had to start full time employment to support his mom and sister, which prevented him from attending and competing in the National Speech Competition, but it did not stop his perseverance and thirst to become a lawyer. In 1973, he was accepted at the University of California at Los Angeles. He received a Bachelor of Arts Degree in Political Science from UCLA in just three years.

In 1976, Bernie was admitted to Hastings College of the Law. At Hastings, he served as Senior Class Student Body Representative. He also served as the Student Body Representative on the Hastings Faculty Standing Committee on Disadvantaged Students and the Hastings Faculty Standing Committee … Read More